The energetic equivalent of purely physical cohesion among dipole-free valence-satisfied molecules of the aliphatic hydrocarbons is about 1/300 down to 1/500 of that of the chemical bond. As a result of the often present asymmetries and polarities one, as a rule, gets 1/100 of that of the chemical bond. These forces are, however, not sufficient to really hold together the bonding partners under normal temperatures. In the case of suitable special-structured molecules, these values may grow significantly (in the case of the loose molecular associations they reach about 1/10 of the value of the chemical bond), but they can never come close to those of the chemical bondings themselves, and if they do, then at the expense of the loosening of other bonds, which then would itself mean [when indeed the energetic value comes close to that of the chemical bond] precisely a transition to chemical bonding itself. Expressed in so-called action ranges, the well-known inter-molecular forces, such as v. d. Waals forces, dipole forces, dispersion forces [such as in colloidal solutions], show at best an action range up to 5 Angstrom, while a ten-fold of it of correspondingly stronger forces of aggregation is needed to explain the securely functioning order phenomena of coherence such as that in micelle formation, protein synthesis, chromosome conjugation, etc. Here Unimol offers all imaginable help, while otherwise one cannot do it without auxiliary constructs. Recall the by Friedrich-Freska discussed possibility of a "zip fastener mechanism" in chromosome conjugation. The pairing could then be explained with inter-molecular forces, insofar both chromosomes have come into contact with each other at some homologous spot [on each partner], after which then further cohesion [cohesion of the rest of each partner] could proceed from the initial place of contact onwards, like it is in a zip. Here [as to the problem -- in the system approach -- of homologous portions coming in contact with each other] Unimol comes to help with its intra-molecular effect, and completes things with what was missing.