The inter-molecular forces may in living systems play an important role insofar as they,- in the case of possible great and strongly anisotropous polarizability of in themselves non-polar molecular regions,- cause, with the already existing strongly polar groups, substantial induction effects while at the same time fixing them. Or that the inter-molecular forces do fix, through interaction, also polarities already present, and in turn being themselves fixed by them.
But the most important role the inter-molecular forces do play undoubtedly there, where it is not about the proper macromolecule [i.e. the living molecule] itself anymore, but about the apposition [deposition] of other molecules, be it to bring it into reaction-distance and thus into a reactive state, or using it as a wall or layer, or to stabilize certain physical features, etc.